False context fear memory in rats
نویسندگان
چکیده
منابع مشابه
Ventral hippocampal muscimol disrupts context-specific fear memory retrieval after extinction in rats.
Research aimed at understanding Pavlovian fear memory extinction has yielded considerable insight into the conditions under which fear memories may become inhibited. After extinction, Pavlovian fear memory retrieval is context-specific. Fear memories are not expressed in the extinction context, but they are expressed in every other context. Research indicates that the dorsal hippocampus mediate...
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Introduction: Protein kinase M zeta (PKMζ) is assumed to be actively involved in retainig long-term potentiation. The goal of this study was to investigate the role of PKMζ in basolateral amygdala (BLA) upon acquisition, consolidation, retention and retrieval of memory using a specific inhibitor of PKMζ. Methods: Sixty male wistar rats underwent stereotaxic surgery and were cannu...
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Context plays a foundational role in determining how to interpret potentially fear-producing stimuli, yet the precise neurobiological substrates of context are poorly understood. In this issue of Cell, Xu et al. elegantly show that parallel neuronal circuits are necessary for two distinct roles of context in fear conditioning.
متن کاملEnsemble coding of context-dependent fear memory in the amygdala
After fear conditioning, presenting the conditioned stimulus (CS) alone yields a context-specific extinction memory; fear is suppressed in the extinction context, but renews in any other context. The context-dependence of extinction is mediated by a brain circuit consisting of the hippocampus, prefrontal cortex (PFC) and amygdala. In the present work, we sought to determine at what level of thi...
متن کاملFalse memory for context and true memory for context similarly activate the parahippocampal cortex.
The role of the parahippocampal cortex is currently a topic of debate. One view posits that the parahippocampal cortex specifically processes spatial layouts and sensory details (i.e., the visual-spatial processing view). In contrast, the other view posits that the parahippocampal cortex more generally processes spatial and non-spatial contexts (i.e., the general contextual processing view). A ...
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ژورنال
عنوان ژورنال: Learning & Memory
سال: 2015
ISSN: 1549-5485
DOI: 10.1101/lm.039065.115